The Department of Emergency Medicine is searching for a highly motivated Research Technician to join the Greineder lab. Their translational research program focuses on the design, implementation, and testing of drug immunotargeting strategies, in which antibodies (or recombinant antibody fragments) are used to deliver drugs and/or drug carriers to specific organs, cells, or even subcellular domains. Projects in the laboratory involve a wide array of techniques -- recombinant protein engineering (molecular biology, protein production and purification), nanoparticle formulation and QA, bioconjugation, HPLC, cell culture assays (binding,internalization, etc), in vivo tracing of radiolabeled proteins and/or drug carriers, and the assessment of therapeutic effects and toxicity in both healthy animals and models of several emergency cardiovascular and inflammatory conditions. The applicant will work closely with the PI and have the opportunity to learn any or all of these techniques. Applicants will not be required to work with radioactive materials if not desired.
The primary responsibilities will be planning and conducting bench experiments, meticulous documentation in physical and/or digital notebooks, and analysis of data (often with the assistance of the PI).
The technician will also be responsible for some lab maintenance activities -- e.g.participating in lab safety self-inspections, autoclaving, identifying/ordering key reagents).
Participation in lab meetings and data presentation are also expected.
Must work effectively in a team setting, be able to communicate well, and keep clear records
Bachelor’s degree and 1-3 years of related experience.
Good work ethic, excellent multitasking skills, and enthusiasm for developing new skills and expertise.
Bachelors’s degree in molecular biology, biochemistry, biology, engineering (BME, ChemE) or related scientific degree, with 2 or more years of experience in laboratory research.
Previous experience with molecular biology (cloning), mammalian or insect cell culture, bacterial culture, protein purification and QC, tissue sectioning, microscopy, and handling of lab animals are all preferred but are not required.
The successful candidate will have a strong work ethic, commitment to the scientific method, excellent organizational and time management skills, enthusiasm for developing new skills and expertise, and willingness to work with and train less-experienced students and technicians.
Full time Monday thru Friday. Flexible schedule with occasional nights and weekends as required for successful completion of experiments.
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Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Job openings are posted for a minimum of seven calendar days. This job may be removed from posting boards and filled anytime after the minimum posting period has ended.
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The University of Michigan is an equal opportunity/affirmative action employer.