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Research Technician Senior

Location
Ann Arbor, MI

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The Garner Laboratory () in the Department of Medicinal Chemistry at the University of Michigan is recruiting a senior-level Research Technician. The Garner Laboratory at the University of Michigan is an interdisciplinary group using chemical biology, medicinal chemistry and molecular and cellular biology approaches for studying microRNA biology and mRNA translation, or protein synthesis. A primary focus is the design and development of innovative high-throughput screening assays for chemical probe discovery. Current areas of investigation include microRNA maturation, microRNA-protein interactions and protein-protein interactions involved in mRNA translation. Our work is supported by the NCI and NIGMS. Responsibilities* The successful candidate will perform high-throughput screening using Garner laboratory developed biochemical assays at the University of Michigan Center for Chemical Genomics. The candidate will also be responsible for the preparation of all necessary assay reagents; examples include the expression and purification of required proteins, RNA labeling, buffers, etc. Additional efforts in small molecule follow-up such as biophysical characterization and biochemical and molecular biology assays will also be required. Required Qualifications* B.S. in biochemistry, chemistry or a related field 2 years of related experience Knowledge and skills in general biochemistry and molecular/cellular biology experience (cloning, protein expression and purification) Excellent organization and communication skills for data management and results dissemination in weekly group meetings Basic skills in word processing, Excel, Prism Desired Qualifications* Biochemical assay experience High-throughput screening experience Background Screening The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks will be performed in compliance with the Fair Credit Reporting Act.

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