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Research Associate

Location
Cambridge, MA

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The Senior Research Associate (title and grade will depend upon experience and education) will join the Integrated Oncology Discovery Research team at Bristol-Myers Squibb in Cambridge, MA and aide in the advancement of early stage therapeutic targets at the intersection of tumor genetics and tumor immune biology.

The qualified candidate is a highly motivated, interactive, and creative individual that possesses the ability to work across a highly matrixed environment to advance preclinical drug development programs from target identification/validation through IND enabling activities. The candidate will be expected to effectively collaborate with colleagues in the oncology, immunology, immuno-oncology, protein engineering/antibody development and medicinal chemistry groups. The successful candidate will demonstrate clear and professional verbal and written communication, capable of presenting scientific results to multidisciplinary teams and key stakeholders.

Qualifications

• A B.S. with a minimum of 5 years of experience, or an M.S. with a minimum of 3 years of academic/industrial experience with strong scientific knowledge and research experience in cancer biology/cellular and molecular biology is required.

• Demonstrated independence in experimental design, execution, data analysis and troubleshooting is required.

• Knowledge of preclinical drug development including knowledge of designing assays and flowcharts to identify and optimize drug candidates is required.

• Hands on experience with a wide range of in-vitro cellular and biochemical assays, including cell culture, western blotting, immunoprecipitation, ELISAs (MSD), reporter assays, siRNA/shRNA knockdown, CRISPR-mediated genome editing, qPCR, cloning, lentivirus generation and transduction is required.

• Experience with in vivo/ex vivo pharmacology, including rodent handling and common procedures including tissue processing is desired. Working knowledge of in-vivo PK, PD and efficacy studies is desirable.

• Experience in data mining through use of desktop tools/interfaces and public databases (e.g., UCSC genome Browser, CBIO, GTex, Oncoland etc) is highly desirable.

• Proficiency in utilizing software such as Graph Pad, Microsoft office etc. for data analysis and figure generation is required.

• Ability to mentor more junior scientists and ease in sharing expertise with colleagues on best practices in the laboratory would be highly valued.

• Attention to detail with excellent organizational and record keeping skills is a requirement.

• Excellent interpersonal skills with the ability to interact effectively with people, internally and externally is required.

• This position is located in Cambridge, MA. There will be less than 10% travel.,identifier:{name:**MEMBERS ONLY**SIGN UP NOW***.,value:R1506665,@type:PropertyValue},datePosted:2018-07-13 00:19:23 00:00,validThrough:2018-08-11 23:00:00 00:00,employmentType:FULL_TIME,hiringOrganization:{name:**MEMBERS ONLY**SIGN UP NOW***.,@id:400424,@type:organization},jobLocation:{name:Cambridge, MA, US,address:{addressCountry:US,addressLocality:Cambridge,addressRegion:Massachusetts,@type:PostalAddress},@type:place},industry:Science/R&D, Research,educationRequirements:Associate Degree,@type:JobPosting,@context:****

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